This route runs from Silverton to the Animas Forks Ghost Town. It follows the Animas River.

Historic sites: Aspen Mine, Mayflower Mill, Howardsville, Middleton, Sunnyside Mill, Eureka, Otto Mear's Snowshed, Animas Forks Ghost Town, Columbus Mill.

Connecting Routes: Cinnamon Pass Road, California Gulch Trail, Corkscrew Gulch Trail, Stony Pass Trail, Maggie Gulch Trail, Minnie Gulch Trail, Picayne Gulch Trail, Eureka Gulch Trail